General body is the apex body of the Council which was being reconstituted in August 2006. It consist of 61 members comprising ministers and secretaries of different state department and head of the departments of water resources, PHE, PWD, Forest, Agriculture, Industry and Technical Education. In addition four vice-chancellors from universities, eminent scientist in science, sociology and medical sciences are nominated as member by the president. Representatives from national level research organization are also nominated.

The General Body :-

1. Chief Minister, Madhya Pradesh. President
2. Vice - President (to be nominated by the President) Vice - President
3. Minister / State Minister / Deputy Minister for Science and Technology, Madhya Pradesh as may be nominated by the President. Member
4. Minister / State Minister / Deputy Minister for Education, Madhya Pradesh as may be nominated by the President. Member
5. Minister / State Minister / Deputy Minister for Finance, Madhya Pradesh as may be nominated by the President. Member
6. Minister / State Minister / Deputy Minister for Industry, Madhya Pradesh as may be nominated by the President. Member
7. Minister / State Minister / Deputy Minister for Agriculture, Madhya Pradesh as may be nominated by the President. Member
8. Minister / State Minister / Deputy Minister for Planning, Madhya Pradesh as may be nominated by the President. Member
9. Chief Secretary, Government of Madhya Pradesh. Member
10. Secretary to Government of Madhya Pradesh, Science and Technology Department. Member
11. Secretary to Government of Madhya Pradesh, Education Department Member
12. Secretary to Government of Madhya Pradesh, Finance Department. Member
13. Secretary to Government of Madhya Pradesh, Planning, Economics and Statistics Department. Member
14. Secretary to Government of Madhya Pradesh, Agriculture Department. Member
15. Secretary to Government of Madhya Pradesh, Commerce and Industry Department. Member
16. Secretary to Government of Madhya Pradesh, Rural Development Department. Member
17. Secretary to Government of Madhya Pradesh, Housing & Environment Department. Member
18. Chairman, Madhya Pradesh Electricity Board. Member
19. Secretary to Government of Madhya Pradesh, Manpower Planning Department. Member
20. Vice Chancellors from the Universities of Madhya Pradesh Member
21. Vice Chancellor , Jawaharlal Nehru Krishi Vishwa Vidhyalaya, Jabalpur. Member
22. Director, Maulana Azad College of Technology, Bhopal. Member
23. Four eminent scientist, to be nominated by the president. Member
24. Two eminent social Scientist , to be nominated by the President. Member
25. Two eminent persons from the medical profession to be nominated by the President. Member
26. Engineer-in-chief, Irrigation, Madhya Pradesh Member
27. Engineer-in-chief, Public Health Engineering, Madhya Pradesh. Member
28. Engineer-in-chief, Public Work Department, Madhya Pradesh. Member
29. Principal Chief Conservator of Forest , Madhya Pradesh. Member
30. Director of Agriculture, Madhya Pradesh. Member
31. Director of Industries, Madhya Pradesh. Member
32. Director of Technical Education, Madhya Pradesh. Member
33. Three progressive agriculturist to be nominated by President- Member
34. Three distinguish industrialist or Manufactures to be nominated by the President Member
35. Two representatives of Public Sector undertakings of the State Government, to be nominated by the President. Member
36. Director of Kishore Bharti, Hosangabad. Member
37. Two representatives of Public Sector undertakings of the Government of India engaged in R&D activities, to be nominated by the President. Member
38. A representative of the Department of Science & Technology, Government of India. Member
39. A representative of C.S.I.R. Government of India. Member
40. A representative of Indian National Science Academy. Member
41. A representative of the Indian Council of Social Science Research. Member
42. A representative of the Indian Council of Agriculture Research. Member
43. A representative of the Indian Council of Medical Research. Member
44. Director General of Madhya Pradesh, Council of Science & Technology. Member-Secretary
45. Eminent scientists from different fields Member